Ting earned his PhD in Cell Biology from Peking University, China in 2016 under the supervision of Professor Hongkui Deng. In his PhD study, he and colleagues originally developed and optimized a robust chemically-induced reprogramming system, which is a novel approach to convert mature cells into a pluripotent state by the induction of small molecules (Zhao et al., Cell, 2015, co-first author). Then, he and colleagues investigated the molecular roadmap of chemical reprogramming by single-cell RNA-sequencing and uncovered new mechanistic insights into the nature of induced pluripotency (Zhao et al., Cell Stem Cell, 2018).
Ting joined Scadden lab in 2017 and is interested in integrating chemical approach and novel culture systems to study malignancies and hematopoietic system. He is now applying chemical tools to understand how cancer cells are blocked in an immature state and to overcome the differentiation blockade in osteosarcoma, the most common primary bone cancer affecting children and young adolescents.