David T. Scadden, MD has been selected as the 2019 recipient of the Donald Metcalf Award from the ISEH. He is the Gerald and Darlene Jordan Professor of Medicine at Harvard Medical, and a Professor of Stem Cell and Regenerative Biology at Harvard University, Co-Founder and Co-Director of the Harvard Stem Cell Institute. David is a hematologist/oncologist at the Massachusetts General Hospital in Boston where he founded and directs the Center for Regenerative Medicine; he previously led the Hematologic Malignancies Program of the MGH Cancer Center. He is an elected member of the National Academy of Medicine, the American Association for the Advancement of Science, the American College of Physicians, a fellow of the American Academy of Arts and Sciences, and is a former member of the Board of External Experts for the National Heart, Lung and Blood Institute and the National Cancer Institute’s Board of Scientific Counselors. David is a highly regarded leader in the ISEH community and has made fundamental contributions to the field of Hematology and Stem Cell Biology through his work in defining the adult HSC regulatory niche within the bone marrow microenvironment, and its relevance to the onset and treatment of hematologic disease.